DESCRIPTION
Agilent 1260 Infinity with Agilent 6420A Triple Quadrupole LCMS MS System
The Agilent 1260 Infinity HPLC-Chip/MS system is based on revolutionary microfluidic chip technology specifically designed for nanospray LC/MS. The system includes Agilent 1260 Infinity Capillary and Nanoflow Pumps, High Performance Micro Autosampler with Thermostat, Chip Cube MS interface, and any Agilent 6000 Series Mass Spectrometer. System control is through either Agilent ChemStation or MassHunter software. Second generation HPLC-Chip technology incorporates a carbon ion implanted filter, improving surface characteristics dramatically for optimal contact and sealing, as well as reducing friction between rotor and polyimide chip. These improvements double chip lifetime, lower the cost per analysis as well as improve chip-to-chip and run-to-run reproducibility. With Agilent’s HPLC-Chip II, the Agilent 1260 Infinity HPLC-Chip/MS system takes you to new levels of nanospray MS reliability, robustness, sensitivity and ease of use, and empowers you to enter new application frontiers:
The Agilent 6420A triple quadrupole LC/MS System is designed to offer superb sensitivity, in a reliable, robust, single point of control of partnered LC/MS and HPLC systems. Built with state of the art components and orthogonal ionization technology, this triple quad LC/MS is low cost to operate, and offers a fast solution for simultaneous quantifying, screening and confirming analyses using triggered MRm, as well as dynamic multiple reaction monitoring.
The MRM function of this triple quad LC/MS helps users avoid false positives with confirmation of compound identification, and reports high sensitivity on each ion transition acquired. The Dynamic MRM function groups MRMs in a time window instead of individual segments and has the ability to quantify up to 4000 compounds, giving users more powerful quantitative methods and robust information.
The Agilent 6420A triple quadrupole LC/MS System is ideal for fields needing quantitative analysis such as forensics, toxicology, food testing, clinical research, pharmaceutical ADME/DMPK studies, and environmental analysis. This LC/MS System is also built for round the clock use, to support labs that need to process large numbers of samples. The updated electronics of this LC/MS System gives you high speed data acquisition, and speedy polarity switching for positive and negative ion analysis. This LC/MS System has a hyperbolic quadrupole design, a high-pressure hexapole collision cell with linear acceleration and an off-axis high energy dynode detector.
ADDITIONAL INFORMATION
Features:
- Screen, confirm and quantify – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation
- Efficient analysis – fast MRM speeds allow for analysis of over 100 overlapping compounds in a given retention time window
- Fast polarity switching for analysis of both positive and negative ions
